Intra-Articular Steroid Therapy in Rheumatoid Arthritis
نویسندگان
چکیده
منابع مشابه
Intra-articular steroid therapy in rheumatoid arthritis.
The introduction of steroid preparations into joint cavities has become a routine method of treating some cases of rheumatoid arthritis. Murdoch and Will (1959a, b) have drawn attention to the persistence of prednisolone trimethyl acetate (P.T.M.A.) in the joint cavity and to its, apparently, purely local effect when administered in this way. Since then, Triamcinolone (T.C.A.), Dexamethasone (D...
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It has been suggested that urokinase may have some value in the management of patients with rheumatoid arthritis (Morotomi and Tatezawa, 1970; Ito and Naito, 1970). This fibrinolytic agent activates plasminogen, converting it to plasmin competitively and reversibly. Thus there is some basis, however speculative, for its use in rheumatoid arthritis-a disease which on several clinical and laborat...
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Eight patients with rheumatoid arthritis received an intra-articular injection of either 50 mg or 100 mg of prednisolone acetate into the knee joint. After the injection plasma levels of prednisolone were measured by radioimmunoassay and plasma cortisol levels were estimated fluorimetrically. Peak prednisolone levels were reached at between 2 and 4 hours after the intra-articular injection at b...
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The potential action of cytotoxic agents such as alkylating drugs and antimetabolites on the immune response and inflammatory process has suggested their trial in the treatment of rheumatic diseases. Nitrogen mustard was tried initially both by intravenous and intra-articular injection in the therapy of rheumatoid arthritis and gave variable responses (Jimenez Diaz, 1951; Jimenez Diaz, Lopez Ga...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1962
ISSN: 0003-4967
DOI: 10.1136/ard.21.2.188